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  • Title: [Influence of ethanol on the in vitro and in vivo drug release from some sustained release tablets (author's transl)].
    Author: Frömming KH, Topaloglu Y.
    Journal: Arzneimittelforschung; 1975; 25(12):1958-64. PubMed ID: 3188.
    Abstract:
    The in vitro and in vivo liberation of acetylsalicylic acid from sustained release tablets in presence of ethanol is described. Simultaneous uptake of 120 ml commercial brandy resulted in a faster release of the active substance from the tablets prepared with Eudragit ret-l (PM), as has been proved by urinary excretion data. These results were supported by experiments with a pH-endoaradio transmitter and by radiography.
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