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  • Title: Cervical lymph node metastasis of ovarian dysgerminoma: A case report with fine needle aspiration cytology.
    Author: Maekawa K, Tokumitsu T, Minematsu E, Noguchi H, Nakamura E, Asada Y, Nakayama T, Sameshima H, Sato Y.
    Journal: Diagn Cytopathol; 2020 Apr; 48(4):356-359. PubMed ID: 31886634.
    Abstract:
    Dysgerminoma is a rare germ cell tumor, accounting for 1% to 2% of all malignant ovarian tumors. Here, we report a case of dysgerminoma diagnosed by aspiration cytology of a cervical lymph node. A 20-year-old woman presented with an abdominal mass and left cervical swelling. CT revealed a large pelvic tumor, along with a nodular lesion on the left side of neck. Fine needle aspiration (FNA) cytology of a cervical lymph node showed large atypical cells and small lymphocytes. Immunocytochemical staining on cell block material revealed that these large tumor cells were positive for placental alkaline phosphatase, D2-40, and c-kit. Dysgerminoma was suggested by FNA cytology. Furthermore, bilateral oophorectomy was performed, and histology confirmed the diagnosis of ovarian dysgerminoma. FNA cytology of metastatic lymph nodes along with immunocytochemistry is a useful tool for diagnosis of dysgerminoma.
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