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Title: Transthyretin cardiac amyloidosis: A treatable form of heart failure with a preserved ejection fraction. Author: Griffin JM, Maurer MS. Journal: Trends Cardiovasc Med; 2021 Jan; 31(1):59-66. PubMed ID: 31889610. Abstract: Cardiac amyloidosis (CA) is considered a rare disease with poor prognosis and limited therapeutic options. However, non-biopsy diagnostic modalities as well as emerging therapies are challenging this long-held belief. Radionuclide bone scintigraphy is increasingly being used in the diagnosis of transthyretin amyloid cardiomyopathy (ATTR-CA). As such, it is expected that the number of patients diagnosed with ATTR-CA will continue to rise. Emerging therapies decrease the progressive morbidity and mortality associated with ATTR-CA. The importance of early recognition of ATTR-CA is imperative as prompt initiation of these novel agents is essential to maximize their therapeutic potential. Herein, we outline the current approach to diagnosis of ATTR-CA and review the therapeutic management of the disease.[Abstract] [Full Text] [Related] [New Search]