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  • Title: Neuromelanin in the substantia nigra of adult horses.
    Author: Cozzi B, Pellegrini M, Droghi A.
    Journal: Anat Anz; 1988; 166(1-5):53-61. PubMed ID: 3189848.
    Abstract:
    The structure and histochemical properties of neuromelanin in the Substantia nigra of the horse were studied by light and electron microscopy. Morphological, histochemical and cytochemical evidences showed the presence of a melanin component in some pigment granules, even if a large quantity of granules displayed only the properties of lipofuscins. Pigment formation in the neurons of the Substantia nigra of the horse may take place through the tyrosine-tyrosinase enzymatic pathway, as shown by positive Dopa-reaction. The results obtained were discussed in reference to the possible use of melanin as a marker for catecholaminergic neurons in the brainstem of the horse.
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