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  • Title: [Effect of gamma-radiation of an extremely high dose on the cerebral cortex of the rat (ultrastructural aspects)].
    Author: Abdrakhmanov AA.
    Journal: Arkh Anat Gistol Embriol; 1988 Jun; 94(6):25-9. PubMed ID: 3190467.
    Abstract:
    For 24 h after total gamma-radiation of mature Wistar male rats (180-210 g) in the dose of 150 Gy, ultrastructural rearrangements of the cerebral sensomotor cortex are presented as small destructive changes in neurons, neuroglia and vascular endothelium. Total combination of the changes in ultrastructure of the blood capillaries and perivascular astrocytes makes it possible to suppose that permeability of the microvascular bed wall is increased. At this period, together with the destructive changes there are evidently certain compensatory-restorative processes, developing in the cerebral tissue. It is possible to suppose that already during the first hours after the radiation the ultrastructural changes of neurons are resulted not only from the direct effect of radiation, but from certain influences of the radiation damage of neuroglia and microvessels.
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