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  • Title: Differential elongation of autosomal pachytene bivalents related to their DNA content in human spermatocytes.
    Author: Luciani JM, Guichaoua MR, Cau P, Devictor B, Salagnon N.
    Journal: Chromosoma; 1988; 97(1):19-25. PubMed ID: 3191793.
    Abstract:
    The establishment of the complete karyotype of human pachytene spermatocytes reveals differences in stretching of chromosomes between meiosis and mitosis. Bivalents or specific regions of bivalents which exhibit many R-bands are particularly elongated. In mitotic chromosomes, the DNA contained in such bands is known to be early replicating. The study of variations in the total length and the centromeric index of bivalent 1 suggests that differential elongation of pachytene bivalents is a premeiotic event, taking place during the last DNA replication.
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