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  • Title: Normal development in Ambystoma mexicanum: A complementary staging table for the skull based on Alizarin red S staining.
    Author: Atkins JB, Houle L, Cantelon AS, Maddin HC.
    Journal: Dev Dyn; 2020 May; 249(5):656-665. PubMed ID: 31930611.
    Abstract:
    BACKGROUND: As the role of Ambystoma mexicanum, or the Mexican axolotl, expands in research applications beyond its traditional use in studies of limb regeneration, a staging table that is more anatomically extensive is required. Here, we describe axolotl skull development as it relates to previously established developmental stages that were based on limb development. RESULTS: We find that most key developmental events in the skull correspond to these previously established stages, creating easily recognizable stages of axolotl throughout skull morphogenesis. CONCLUSIONS: With this complementary staging table in hand, researchers can stage axolotl larvae when limb data are missing or incomplete, or when cranial data alone is available.
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