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  • Title: [Conditioned reflex activity in the aging process in white rats].
    Author: Mering TA.
    Journal: Zh Vyssh Nerv Deiat Im I P Pavlova; 1988; 38(4):667-74. PubMed ID: 3195226.
    Abstract:
    In Wistar rats, irrespectively of their age, conditioned reflexes to present stimuli are preserved and elaborated. Neither the mechanism of time intervals estimation is disturbed in aged and old rats (24-32 months). Long intervals between experiments (3-5 months) do not influence their state. Distinct changes are revealed of spatial-temporal differentiations in T-maze: significant worsening of their state is observed in 8-10 months age; in this age it is neither possible to elaborate them again. In simplified experimental conditions in the T-maze the old rats preserve the spatial orientation.
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