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  • Title: Effects of endurance exercise on carnitine palmitoyltransferase I from rat heart, skeletal muscle and liver mitochondria.
    Author: Guzmán M, Castro J.
    Journal: Biochim Biophys Acta; 1988 Dec 16; 963(3):562-5. PubMed ID: 3196751.
    Abstract:
    Prolonged physical exercise increased the activity of carnitine palmitoyltransferase I in rat heart and skeletal muscle mitochondria, whereas enzyme sensitivity to inhibition by malonyl-CoA remained unchanged. Nevertheless, inhibition of carnitine palmitoyltransferase I activity by small decreases in pH was attenuated in heart and skeletal muscle mitochondria from exercised animals. Liver enzyme did not suffer any alteration by endurance exercise.
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