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  • Title: [Phenotypic correction of the immune response by L-tyrosine in mice reacting oppositely to sheep erythrocytes].
    Author: Lebedev VV, Titov MI, Maksimova GF, Portnova AP, Molokoedov AS.
    Journal: Biull Eksp Biol Med; 1988 Nov; 106(11):583-5. PubMed ID: 3196860.
    Abstract:
    The possibility of transversion of low-reacting mice into high-reacting ones evaluated by the application of the natural immunostimulators. L-tyrosine and thymic polypeptides (taktivin) were compared by their ability for the phenotypical correction of the immune response of the oppositely reacting mice. It was established that under the application of L-tyrosine to oppositely reacting mice the phenotypical correction of the immune response is possible. The dramatic increase in AFC and the AFC-SI secreting IgM is observed in the mice, low-reacting to SRBC in comparison with the high-reacting lines.
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