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Title: Characterization of a sequence of human T cell leukemia virus type I from a patient with chronic progressive myelopathy. Author: Kwok S, Kellogg D, Ehrlich G, Poiesz B, Bhagavati S, Sninsky JJ. Journal: J Infect Dis; 1988 Dec; 158(6):1193-7. PubMed ID: 3198935. Abstract: DNA from peripheral blood mononuclear cells of individuals with chronic progressive myelopathy (CPM) were extensively analyzed for the presence of human T cell leukemia virus (HTLV) type I-like sequences by using the polymerase chain reaction. The DNA samples were amplified with oligonucleotides from three separate regions of HTLV viral genomes. A portion of the amplified viral genome from a representative patient was sequenced after molecular cloning into bacteriophage M13. Sequence data indicate that HTLV type I and not a related virus is associated with CPM.[Abstract] [Full Text] [Related] [New Search]