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  • Title: Interferon-beta induced remission in a hairy cell leukemia patient resistant to interferon-alpha.
    Author: Michalevicz R, Aderka D, Frisch B, Revel M.
    Journal: Leuk Res; 1988; 12(10):845-51. PubMed ID: 3199843.
    Abstract:
    Two patients with advanced hairy cell leukemia and pancytopenia responded successfully to intramuscular injections of recombinant interferon-beta, with normalisation of blood counts. One of the patients had developed resistance to interferon-alpha. The in-vivo response was predicted by in-vitro studies showing a beneficial effect of IFN-beta on erythropoiesis in cell cultures derived from these patients.
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