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  • Title: Lyciiterpenoids A-D, four new rearranged eudesmane sesquiterpenoids from Lycii Cortex.
    Author: Huang YP, Xia Z, Xu W, Xu TQ, Zhang HX, Zhou GX.
    Journal: Nat Prod Res; 2021 Nov; 35(21):3625-3633. PubMed ID: 32000527.
    Abstract:
    Four new rearranged eudesmane sesquiterpenoids, Lyciiterpenoids A-D (1-4), together with four known compounds (5-8) were isolated from the aqueous extract of Lycii Cortex. Their structures were elucidated by spectroscopic analysis, and the absolute configurations of compounds 1-4 were determined by the quantum chemical ECD calculations. The absolute configuration of 1 was further confirmed by X-ray crystallographic data analysis. All the isolated compounds were evaluated for their cytotoxicity against three human cancer cell lines (MCF-7, HepG2, and A549). However, no significant activities were detected even with a concentration up to 100 μM.
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