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  • Title: Fatal Stevens-Johnson syndrome following urography with iopamidol in systemic lupus erythematosus.
    Author: Savill JS, Barrie R, Ghosh S, Muhlemann M, Dawson P, Pusey CD.
    Journal: Postgrad Med J; 1988 May; 64(751):392-4. PubMed ID: 3200783.
    Abstract:
    A 46 year old white woman with active systemic lupus erythematosus developed a skin rash 8 hours after intravenous urography with the non-ionic contrast medium iopamidol. Severe Stevens-Johnson syndrome with erythema multiforme, intrahepatic cholestasis, pulmonary infiltrates and acute renal failure ensued, leading to her death. Although non-ionic contrast media are generally less toxic than traditional ionic agents, their use in patients with immunological disease may be hazardous.
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