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  • Title: Current strategy for donor-specific blood transfusions including a pre- and post transplant role for azathioprine.
    Author: Salvatierra O.
    Journal: Transplant Proc; 1988 Dec; 20(6 Suppl 8):37-41. PubMed ID: 3201558.
    Abstract:
    The optimal use of the DST protocol has been defined with a preference for the protocol in patients undergoing a first transplant with a low pre-DST PRA. Azathioprine coverage during DST administration in this group assures a low sensitization rate. In addition, a posttransplant immunosuppressive protocol is introduced that includes very low-dosage P and Cs therapy along with limited-dose Aza. Preliminary results appear to indicate that this may possibly further improve graft survival; but, most importantly, it will reduce problems and complications associated with steroid and Cs therapy.
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