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  • Title: SANTAMARINE: Mechanistic studies on multiple diseases.
    Author: Jalal S, Ahmad B, Zhang T, Guo L, Huang L.
    Journal: Chem Biol Drug Des; 2020 Apr; 95(4):427-434. PubMed ID: 32022458.
    Abstract:
    Medicinal plants are vital sources of modern and traditional Chinese medicines. Sesquiterpene lactones (SLs) consist of a large group of plant secondary metabolites and belong to C15 terpenoid group. SLs have shown various biological activities including antitumor and anti-inflammatory activities. Santamarine (STM), C15 H20 O3 , is a kind of sesquiterpene lactone, whose molecular weight is 248.322 g/mol. Santamarine has been isolated from several plants species and has shown eminent biological activities, such as anticancer activity and anti-inflammatory activity. In this mini-review, we summarize the studies on the effects and the mechanisms of STM, and explore the avenues of application.
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