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  • Title: [Aspects of the morphogenesis of cancer of the endometrium].
    Author: Frank GA, Belous TA, Sokolova NV.
    Journal: Arkh Patol; 1988; 50(9):40-6. PubMed ID: 3202700.
    Abstract:
    The paper covers a number of morphogenetic problems of endometrial cancer with reference to multidirectional differentiation of the uterine epithelium affected by tumor. Metaplastic changes of the endometrium observable in three basic variants (tubal, endocervical, squamous cell) can entail dysplasia with resultant malignant transformation. Endometrial cancer shows complex structure of the tumor with sings of multidirectional epithelial differentiation: endometrial, tubal, endocervical, squamous). Morphological features of the tumor and adjacent mucosa, assessed comparatively, suggest a close relationship between the direction of endometrial epithelium differentiation and the new growth histological structure.
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