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  • Title: [Use of a xenogeneic collagen matrix on extraction sockets: a new approach in ARONJ prevention (in german)].
    Author: Kuster I, Valdec S, Rücker M, Bichsel D.
    Journal: Swiss Dent J; 2020 Feb 10; 130(2):139-145. PubMed ID: 32031353.
    Abstract:
    Antiresorptive drugs are increasingly used for the treatment of osteoporosis, various bone pathologies and malignant tumors. Antiresorptive agent-related osteonecrosis of the jaw (ARONJ) is a relevant complication, especially in nonhealing extraction sockets. Prescription of antibiotics in combination with a safely guaranteed closure of the extraction socket is considerably reducing the risk of ARONJ development. Full mucosal coverage usually requires the formation of a full thickness flap, which involves periosteal disclosure of the remodeled bone. In this new approach, primary wound closure is performed by covering the extraction socket with a xenogeneic collagen matrix. Ultimately, elevation of a periosteal flap and additional exposure of the surrounding alveolar bone is avoidable. The technique is exemplified on a patient case with a perennial anti resorptive medication history.
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