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  • Title: The effects of four drug regimens on sister chromatid exchange frequency in patients with lymphomas.
    Author: Brown T, Dawson AA, Bennett B, Moore NR.
    Journal: Cancer Genet Cytogenet; 1988 Nov; 36(1):89-102. PubMed ID: 3203299.
    Abstract:
    Patients undergoing first-line chemotherapy after diagnosis of lymphoma have considerable DNA damage in their peripheral blood lymphocytes, using sister chromatid exchange (SCE) frequency as a sensitive indicator. Different drug regimens produce different patterns of changes in SCE frequency. These may be related to their potential to induce second malignancies.
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