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  • Title: Isolated Intracranial Rosai-Dorfman Disease: Case Report and Review of the Literature.
    Author: Boissaud-Cooke MA, Bhatt K, Hilton DA, Muquit S.
    Journal: World Neurosurg; 2020 May; 137():239-242. PubMed ID: 32035213.
    Abstract:
    BACKGROUND: Rosai-Dorfman disease (RDD) is a rare idiopathic benign proliferative disorder of histiocytes, predominantly affecting the lymph nodes. RDD can also present in extranodal tissues and is occasionally found within the central nervous system. CASE DESCRIPTION: We report the case of a 52-year-old man presenting with a short episode of dizziness. Imaging identified a right frontal, extraaxial, dural-based lesion, suspicious for a meningioma. The patient underwent a craniotomy for tumor resection and, although not entirely typical, the pathology was consistent with RDD. No other evidence of RDD was identified. CONCLUSIONS: RDD should be considered as a differential diagnosis of dural-based lesions, more commonly meningiomas.
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