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  • Title: Immunological response of patients with tumors of the urogenital tract: a follow-up of cell-mediated antitumor immunity by the LAI test.
    Author: Holán V, Heyberger K, Bubeník J, Hasek M, Kanka J, Laurová L.
    Journal: Neoplasma; 1977; 24(1):71-9. PubMed ID: 320490.
    Abstract:
    Antigen-induced inhibition of leukocyte adherence is a suitable method providing information on immunological response of the tumor bearers. Leukocytes from patients' blood were tested by an in vitro method to detect cell-mediated antitumor immunity. Positive reactions of leukocytes to the specific antigen were found in carcinoma of the uterine cervix, vulva and ovary in 13 patients. The modified LAI test evaluated on the basis of free cells in Eagle's medium using the specific antigen is a simplified reversed method which, however, keeps the specificity.
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