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  • Title: Age related occurrence of natural agglutinins in the erisilkworm, Philosamia ricini.
    Author: el Moataz Bellah M, el Ridi R, Abou-Elela R, Cooper EL.
    Journal: Dev Comp Immunol; 1988; 12(4):707-17. PubMed ID: 3208956.
    Abstract:
    Natural agglutinins against human, guinea pig, and rat erythrocytes (RBC) and bacteria Bacillus thuringiensis were readily detected in hemolymph of final instar larvae with resulting titers of 0-9 (log2). Titers were independent of sex and season but varied conspicuously and reproducibly with age. Moreover, response of hemagglutinins to heating varied with age being heat-labile in younger larvae, yet totally resistant to heating for 30 min at 70 degrees C in older ones. Bacterial agglutinins were uniformly resistant at all larval ages. The study thus reveals that the amounts and physico-chemical properties of P. ricini agglutinins change with larval development. Therefore, larval age should be taken into close consideration before reporting on the occurrence and properties of agglutinins in insects.
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