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  • Title: Metagenomics of Imported Multidrug-Resistant Mycobacterium leprae, Saudi Arabia, 2017.
    Author: Guan Q, Almutairi TS, Alhalouli T, Pain A, Alasmari F.
    Journal: Emerg Infect Dis; 2020 Mar; 26(3):615-617. PubMed ID: 32091380.
    Abstract:
    Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations in rpoB and rrs corresponding to the multidrug-resistance phenotype clinically observed. Metagenomics sequencing can be used to identify multidrug-resistant M. leprae.
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