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  • Title: Nucleolar organizer regions in melanocytic dysplasia and melanoma.
    Author: Fallowfield ME, Dodson AR, Cook MG.
    Journal: Histopathology; 1988 Jul; 13(1):95-9. PubMed ID: 3209193.
    Abstract:
    Using silver (Ag) staining to demonstrate nucleolar organizer region-associated proteins (AgNORs), pigmented naevi exhibiting features of melanocytic dysplasia have been examined and compared with benign intradermal and compound naevi and with malignant melanomas. A highly significant difference was found between the numbers of AgNORs demonstrated in benign naevus cells and atypical melanocytes and in malignant melanocytes, suggesting that this technique may have a role in differentiating between difficult melanocytic lesions.
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