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  • Title: Electrochemical Impedance Characterization of Blood Cell Suspensions-Part 2: Three-Phase Systems With Single-Shelled Particles.
    Author: Zhbanov A, Yang S.
    Journal: IEEE Trans Biomed Eng; 2020 Oct; 67(10):2979-2989. PubMed ID: 32091989.
    Abstract:
    The analyses presented in Part 1 are expanded to three-phase composite materials. The theory developed in Part 1 is used for analytical and numerical calculations of dielectric spectra. In this study, three-phase systems with single-shelled particles were considered. The disordered particle distribution, aligned orientation of particles, and particles placed in different lattice structures are studied. It is shown that both two-phase and three-phase composites exhibit β-dispersion, while three-phase composites additionally exhibit δ-dispersion. This is the fundamental difference in the spectra for two- and three-phase materials. In the case of aligned orientation, the effective permittivity in the direction perpendicular to the spheroid plane exhibits a maximum at a volume fraction of approximately 0.5. Both two- and three-phase materials display this behavior. This may be of interest for the development of new metamaterials. The dielectric properties of composite materials with random distribution and periodic arrangement of particles differ significantly. The dielectric spectrum of erythrocyte suspension in plasma was measured by means of electrochemical impedance spectroscopy. The measurement system consisted of a small chamber with two planar electrodes placed at the bottom and an impedance analyzer. The dielectric properties of erythrocyte cytoplasm and membrane were numerically determined based on experimental data. The measurement of the dielectric properties of whole blood and blood components is very promising for various medical applications.
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