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  • Title: Psychiatric and Medical Profiles of Autistic Adults in the SPARK Cohort.
    Author: Fombonne E, Green Snyder L, Daniels A, Feliciano P, Chung W, SPARK Consortium.
    Journal: J Autism Dev Disord; 2020 Oct; 50(10):3679-3698. PubMed ID: 32096123.
    Abstract:
    This study examined lifetime medical and psychiatric morbidity reported by caregivers of 2917 autistic adults participating in the US research cohort SPARK. Participants were 78.4% male, 47.3% had intellectual disability, and 32.1% had persistent language impairments. Childhood language disorders (59.7%), speech/articulation problems (32.8%), sleep (39.4%) and eating problems (29.4%), motor delays (22.8%) and history of seizure (15.5%) were the most frequently reported clinical features. Over two thirds (67.2%) had been diagnosed with at least one psychiatric disorder (anxiety disorders: 41.1%; ADHD: 38.7%). Compared to verbally fluent participants, those with language impairments had lower frequencies of almost all psychiatric disorders. Female sex and older age were associated with higher medical and psychiatric morbidity.
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