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  • Title: Cytology in the diagnosis of pancreatic cancer.
    Author: Del Favero G, Fabris C, Angonese C, Basso D, Rebuffi A, Costantin G, Matarazzo R, Di Mario F, Naccarato R.
    Journal: Int J Pancreatol; 1988; 3 Suppl 1():S137-41. PubMed ID: 3209868.
    Abstract:
    The study of cytology in duodenal and/or pure pancreatic juice has been proposed in the differential diagnosis of pancreatic cancer. In our experience the sensitivity of cytology in duodenal juice, collected during Secretin-Cholecystokinin test, in diagnosing pancreatic cancer was 66.6%. False positive results were obtained only rarely (1.4%) in patients with chronic pancreatitis and benign diseases of the gastrointestinal tract. The cytological evaluation of pure pancreatic juice, obtained by ERCP, increases sensitivity up to 80-90%, especially when the combination of the results of ERCP and cytology is performed. Cytological examination of duodenal and/or pure pancreatic juice is a useful tool in detecting pancreatic malignancy and in differential diagnosis with chronic pancreatitis.
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