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  • Title: [Gaba-activated conductance of isolated neurons of rat cerebellum and sensory ganglia].
    Author: Valeev AE, Chernevskaia NI.
    Journal: Neirofiziologiia; 1988; 20(5):645-52. PubMed ID: 3211229.
    Abstract:
    Results of the study of GABA-activated ion currents on single isolated neurons of rat were obtained by means of voltage-clamp, intracellular perfusion and "concentration clamp" methods. The reversion potential of GABA-activated current corresponded to the equilibrium potential for Cl ions as it was determined by the Nernst equation. The dose-response relationship was activated by a single GABA molecule (Kd = 1.4.10(-4) mol/l). GABA-activated currents were blocked by bicuculline methoiodide and isocoryne.
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