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  • Title: Tuberculous Spondylitis Caused by Intravesical Bacillus Calmette-Guerin Therapy.
    Author: Minakata T, Nakano Y, Tamura S, Kazuki Y, Hayakawa K, Hayakawa T, Oota T, Fuzimoto T, Yamano Y, Takii T.
    Journal: Intern Med; 2020; 59(5):733-737. PubMed ID: 32115520.
    Abstract:
    A 74-year-old man underwent intravesical bacillus Calmette-Guerin (BCG) therapy for bladder cancer and later presented with lower left back pain. Magnetic resonance imaging of the spine showed high signal intensity, diagnosed as a cystic lesion in the epidural and bilateral intestinal psoas muscle. A computed tomography-guided needle biopsy and histological examination revealed bacteria from the family Mycobacteriaceae, and Mycobacterium bovis was identified using multiplex polymerase chain reaction. If lower back pain appears in a patient who has undergone BCG therapy, it is necessary to test for tuberculous spondylitis. In addition, QuantiFERON is useful for the differential diagnosis of M. bovis BCG infection.
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