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  • Title: [A Case of Surgical Resection of an Esophageal Gastrointestinal Stromal Tumor after Neoadjuvant Therapy with Imatinib].
    Author: Nishida Y, Takeda S, Kanekiyo S, Shindo Y, Matsukuma S, Matsui H, Tokumitsu Y, Tomochika S, Iida M, Suzuki N, Yoshino S, Hazama S, Ueno T, Nagano H.
    Journal: Gan To Kagaku Ryoho; 2019 Dec; 46(13):2449-2451. PubMed ID: 32156961.
    Abstract:
    A 64-year-old man presented with dysphagia. Esophagogastroduodenoscopy revealed a submucosal tumor of 52mm in size at the lower thoracic esophagus. Biopsy yielded a pathological diagnosis of c-kit-positive esophageal gastrointestinal stromal tumor(GIST). We started neoadjuvant therapy with imatinib to avoid excessive surgical invasion. After 6 months of treatment, CT revealed a reduction in tumor size to 27 mm. We performed laparoscopic lower esophagectomy, proximal gastrectomy, double-tract reconstruction, and complete tumor resection. Neoadjuvant imatinib therapy was effective for the esophageal GIST.
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