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  • Title: Clonazolam a new designer benzodiazepine intoxication confirmed by blood concentration.
    Author: Sommerfeld-Klatta K, Łukasik-Głębocka M, Teżyk A, Panieński P, Żaba C, Zielińska-Psuja B.
    Journal: Forensic Sci Int; 2020 May; 310():110237. PubMed ID: 32172178.
    Abstract:
    BACKGROUND: Recently the number of new psychoactive substances have significantly increased, becoming popular among experienced users of designer drugs. A significant group includes benzodiazepine derivatives, which have not been introduced as medications but are abused by people experimenting with new and classical psychoactive substances. CASE PRESENTATION: The aim of this paper was to present the case of a clonazolam ingestion by a person who was not habituated to benzodiazepines. The intake caused only prolonged coma, decreased muscle tone, and deep tendon reflexes without any other concomitant toxicity and cardio-respiratory failure. CONCLUSIONS: Clonazolam concentrations in patient's blood, measured three times were 0.077 mg/L, 0.015 mg/L, 0.009 mg/L after 4, 8 and 12 h, respectively. Clonazolam's human toxicity has not been well established, so any case of poisoning should be closely monitored.
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