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  • Title: [Lipids of blood and erythrocyte membranes in healthy persons and in patients with diffuse toxic goiter, residing in the European North of the USSR].
    Author: Shatsova EN, Danilova RI, Zazhigina RN.
    Journal: Ter Arkh; 1988; 60(9):47-50. PubMed ID: 3217880.
    Abstract:
    A study of the blood plasma content of total cholesterol in 575 healthy persons and 675 patients with diffuse toxic goiter (DTG), and the content of total lipids and triglycerides in 52 healthy persons and 132 DTG patients showed the development of adaptation hyperlipidemia in persons living long in the North. It was preserved in DTG patients irrespective of the gravity of thyrotoxicosis, stages of its therapy and the patients' age. Basing on the analysis of the level of lipid indices of erythrocytic membrane malonic dialdehyde and their refractoriness to peroxide hemolysis in 52 healthy persons and 53 DTG patients, a conclusion was made of excessive stable activation of lipid peroxidation biomembranes which can underlie the development of visceral complications.
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