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  • Title: [Combination antimetabolite-alkylating agent-vinblastine in the treatment of advanced breast cancer].
    Author: Pipino G, Germiniani R, Lavorato F.
    Journal: Minerva Med; 1977 Mar 17; 68(13):835-7. PubMed ID: 321990.
    Abstract:
    The results obtained in 14 patients suffering from hormone-resistant metastatic breast cancer treated with the following association: methotrexate (5-fluorouracyl in case of methotrexate intolerance), cyclophosphamide, vinblastin administered i.v. once every 10-13 days, are reported. 4 objective regression (29%) were observed but survival did not very appreciably differing therapy. In 9 cases (65%) intolerance of various types was observed but in 8 these signs regressed in a short time and the therapy was resumed.
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