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Title: Chromosomal distribution of the RTVL-H family of human endogenous retrovirus-like sequences. Author: Fraser C, Humphries RK, Mager DL. Journal: Genomics; 1988 May; 2(4):280-7. PubMed ID: 3220471. Abstract: We have analyzed the chromosomal distribution of a large family of human endogenous retrovirus-like sequences termed RTVL-H. In situ hybridizations suggest that these sequences are found on all human chromosomes. These results also indicate that clusters or concentrations of RTVL-H elements may exist on chromosomes 1p and 7q. Southern blotting experiments using somatic cell hybrids containing either the human chromosome 3 or the X chromosome confirm the presence of multiple dispersed RTVL-H sequences on these two chromosomes. These experiments also demonstrate that distinct RTVL-H banding patterns can be detected for each chromosome. Thus, RTVL-H probes may be useful in genome mapping studies.[Abstract] [Full Text] [Related] [New Search]