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  • Title: Localization of the gene encoding human factor V to chromosome 1q21-25.
    Author: Wang H, Riddell DC, Guinto ER, MacGillivray RT, Hamerton JL.
    Journal: Genomics; 1988 May; 2(4):324-8. PubMed ID: 3220473.
    Abstract:
    The gene encoding human coagulation Factor V (FV), one of the cofactors in the blood clotting process, has been mapped to chromosome 1 by both Southern hybridization to DNA from human-hamster somatic cell hybrids and in situ hybridization. The whole plasmid pUC3A containing a 1.5-kb cDNA sequence for FV was 32P-labeled for Southern analysis and 3H-labeled for in situ hybridization to metaphase chromosomes. The results localized the FV gene to the region of 1q21-25.
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