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  • Title: [How sensitive and specific is the determination of gliadin antibodies in the serum of patients with severe damage of small intestine mucosa?].
    Author: Hebel E, Piske-Keyser K, Otten A, Wolf H.
    Journal: Monatsschr Kinderheilkd; 1988 Aug; 136(8):459-61. PubMed ID: 3221894.
    Abstract:
    Serum antigliadin antibodies of the IgG- and IgA-class were investigated by an ELISA-test in healthy children, children suffering from coeliac disease and children with recurrent diarrheas. The sensitivity and specificity of positive antibody-titres for the diagnosis of coeliac disease were evaluated. The investigation of antigliadin antibodies proved to be a useful instrument for the diagnosis of acute coeliac disease as well as for the follow-up of such patients. The limitations of this method are pointed out.
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