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  • Title: [Effect of neurotizing exposures on conditioned reflex activity in the late postresuscitation period in rats].
    Author: Nezlina NI.
    Journal: Zh Vyssh Nerv Deiat Im I P Pavlova; 1988; 38(5):952-7. PubMed ID: 3223079.
    Abstract:
    In white rats resuscitated after 10-minutes stop of the blood circulation, conditioned switching over was elaborated on the basis of alimentary and defensive instrumental reflexes and the effect was studied of neurotizing influences. Single application of electrocutaneous pain stimulus in alimentary situation ("collision") led to more expressed disturbances of conditioned activity in resuscitated rats than in intact ones. Differentiation of a signal different from the positive conditioned stimulus only by the height of the tone, was practically not elaborated in resuscitated rats, and the disturbance of the conditioned alimentary reflex to the reinforced signal appearing during differentiation elaboration, was manifest in them to a greater degree. The obtained data testify that even a short-time brain ischemia, accompanied by a fast and full restoration of the neurological status, leads to functional defects of the CNS appearing at subsequent neurotic influences.
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