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  • Title: Multifunctional spherical gold nanocluster aggregate@polyacrylic acid@mesoporous silica nanoparticles for combined cancer dual-modal imaging and chemo-therapy.
    Author: Wu X, Li L, Zhang L, Wang T, Wang C, Su Z.
    Journal: J Mater Chem B; 2015 Mar 28; 3(12):2421-2425. PubMed ID: 32262118.
    Abstract:
    Multifunctional spherical aggregated gold nanoclusters encapsulated by polyacrylic acid/mesoporous silica shell nanoparticles (A-AuNC@PAA/mSiO2 NPs) with aggregation enhanced fluorescence (AEF) properties were fabricated by a facile and reproducible synthetic strategy. The as-prepared NPs were employed as novel theranostic agents for synergistic fluorescence/X-ray computed tomography imaging and chemo-therapy of liver cancer in vitro and in vivo.
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