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  • Title: Pigmentation of glucocorticoid-induced cataractous lenses of developing chick embryos on heating.
    Author: Nishigori H, Iwatsuru M, Hikida M.
    Journal: Curr Eye Res; 1988 Oct; 7(10):989-93. PubMed ID: 3229125.
    Abstract:
    Cataractous lenses produced by hydrocortisone or prednisolone treatment in developing chick embryos turned golden brown on heating at 100 degrees C for 60 min. Analysis of an 80% ethanol fraction from the lenses, which contained the pigment-forming substance(s), demonstrated that the heat-induced pigmentation was related to the appearance of opacity of the lens after glucocorticoid administration and suggested that the pigmentation occurred by the Maillard reaction between glucose and amino acids.
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