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  • Title: Albendazole treatment of human cystic echinococcosis.
    Author: Todorov T, Vutova K, Petkov D, Mechkov G, Kolev K.
    Journal: Trans R Soc Trop Med Hyg; 1988; 82(3):453-9. PubMed ID: 3232185.
    Abstract:
    The effect of albendazole was investigated in 20 patients with single or multiorgan hydatid cyst disease. Albendazole was used at a dose of 10 mg/kg daily in cycles of 28 d for four cycles with 15 d between cycles. Follow-up ranged from 12-18 months. Response varied according to the organ involved, the most successful results being with liver and peritoneal cysts. A positive response was seen in 47% of 34 cyst sites and a partial response was seen in a further 38% of sites. Overall response was classed as completely successful in 30% of patients, and partially successful in 60% at the end of follow-up. Adverse events were rare, although occasional abnormalities of liver function were seen.
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