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  • Title: Propranolol-resistant infantile hemangioma successfully treated with sirolimus.
    Author: Dávila-Osorio VL, Iznardo H, Roé E, Puig L, Baselga E.
    Journal: Pediatr Dermatol; 2020 Jul; 37(4):684-686. PubMed ID: 32323340.
    Abstract:
    Infantile hemangiomas are the most common benign vascular tumors in childhood. Propranolol is the first-line treatment for infantile hemangiomas, but failures may occur. Sirolimus, an mTOR inhibitor, is a promising drug for the treatment of vascular malformations and vascular tumors. We present the case of a child with multiple infantile hemangiomasthat was successfully treated with sirolimus and propranolol after failure of combined propranolol and prednisolone treatment.
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