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  • Title: Performance of the Cytobrush in patients at risk for cervical pathology: does it add anything to the wooden spatula?
    Author: Van Erp EJ, Blaschek-Lut CH, Arentz NP, Trimbos JB.
    Journal: Eur J Gynaecol Oncol; 1988; 9(6):456-60. PubMed ID: 3234423.
    Abstract:
    In 130 high-risk patients for cervical pathology paired smears were obtained with a wooden spatula and a Cytobrush. The Cytobrush was useful in lowering the amount of inadequate smears (2 vs 22%, p less than or equal to 0.01), and detected more abnormal cytology in combination with the spatula compared to the spatula smear alone (27 vs 35%, p less than or equal to 0.05). In 6 cases, adequate false-negative spatula smears, containing endocervical cells, were corrected by the Cytobrush. It is concluded that the Cytobrush is useful in lowering the amount of inadequate smears and false-negative cytology, while there is little evidence of false-positive cytology. The use of the wooden spatula/Cytobrush-combination is recommended in high risk populations.
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