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  • Title: Progression of hypertrophic into a dilated left ventricle in Friedreich's ataxia.
    Author: Casazza F, Morpurgo M.
    Journal: G Ital Cardiol; 1988 Jul; 18(7):615-8. PubMed ID: 3234661.
    Abstract:
    The authors describe the case of a girl who developed Friedreich's ataxia at, approximately, the age of 7, with evidence of cardiac involvement being detected by electrocardiography and echocardiography at a later date. Cardiac function was moderately impaired and remained unchanged for a number of years, during which a picture of hypertrophic left ventricle seemed to be firmly established. Later still, however, the cardiac situation shifted gradually toward a hypokinetic form of the disease, with a progressive thinning of the interventricular septum and posterior wall of the left ventricle, associated enlargement of the ventricular chambers and increasingly severe hypokinesia leading to repeated episodes of heart failure.
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