These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Water-lipid interactions in native bone by high-resolution solid-state NMR spectroscopy.
    Author: Tiwari N, Rai R, Sinha N.
    Journal: Solid State Nucl Magn Reson; 2020 Jun; 107():101666. PubMed ID: 32371298.
    Abstract:
    The study of structural and dynamical properties of lipid and its associated interaction with different components of bone is essential to understand its role at a different level of bone homeostasis such as bone mineralization and bone metabolism. In this article, we present water-dependent dynamical changes observed in lipids (triglycerides) in its absolute native environment inside bone by high-resolution 1H solid-state nuclear magnetic resonance spectroscopy (ssNMR). Relaxation measurement (T2 measurement) ssNMR experiments were performed at different levels of water network induced by dehydration and H/D exchange in native bone. Our measurements reflect the changes in the local environment and dynamical properties of triglyceride due to different hydration levels. The present study explains the role of water in stabilizing the structural properties of triglycerides in bone hence will help understand its pathological role associated with bone physiology and bone disorders.
    [Abstract] [Full Text] [Related] [New Search]