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  • Title: Simultaneous occurrence of cutaneous mastocytosis and juvenile xanthogranuloma in a child: Random or true association?
    Author: Vergara-de-la-Campa L, Torrelo A, Isabel Sánchez-Moya A, Recuero-Pradillo M, Mollejo M, Matito A.
    Journal: Pediatr Dermatol; 2020 Jul; 37(4):716-720. PubMed ID: 32372415.
    Abstract:
    Juvenile xanthogranuloma (JXG) and cutaneous mastocytosis (CM) are two distinct conditions that have rarely been reported in association. We report a child with CM and disseminated JXG, who showed a significant decrease in serum tryptase levels and regression of JXG lesions over time. Due to the paucity of reports, a true association between these two conditions has not been validated, although a potential induction of histiocytic lesions by mast cell degranulation has been proposed.
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