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  • Title: Colonic Basidiobolomycosis-An Unusual Presentation of Eosinophilic Intestinal Inflammation.
    Author: Kurteva E, Bamford A, Cross K, Watson T, Owens C, Cheng F, Hartley J, Harris K, Johnson EM, Lindley K, Levine S, Köglmeier J.
    Journal: Front Pediatr; 2020; 8():142. PubMed ID: 32373558.
    Abstract:
    Basidiobolomycosis is a rare fungal disease caused by Basidiobolus ranarum. Involvement of the gastrointestinal tract is unusual and poses both a diagnostic and therapeutic challenge, as clinical signs are non-specific and predisposing risk factors are lacking. It can mimick inflammatory bowel disease, primary immunodeficiency, or a malignancy and should be considered in patients who do not respond to standard therapy. We present the case of a 22 months old boy with confirmed colonic Basidiobolomycosis, who presented with severe eosinophilic inflammation of the gastrointestinal tract. Panfungal PCR performed on DNA extracted directly from a tissue sample confirmed the presence of Basidiobolus. He made a full recovery with a combination of surgery and prolonged targeted antifungal medication.
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