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  • Title: EEG sleep studies in patients with generalized anxiety disorder.
    Author: Papadimitriou GN, Kerkhofs M, Kempenaers C, Mendlewicz J.
    Journal: Psychiatry Res; 1988 Nov; 26(2):183-90. PubMed ID: 3237912.
    Abstract:
    Sleep polygraphic recordings were performed during 3 consecutive nights in 12 inpatients with generalized anxiety disorder (GAD) in comparison with age- and sex-matched groups of patients with major depressive disorder (MDD) and normal subjects. GAD patients differed significantly from those with MDD. A lower number of awakenings and stage shifts in night 1 and the mean of the 3 nights and a shorter rapid eye movement (REM) duration in night 1 but longer REM latency in the mean of the 3 nights were observed in GAD in comparison to MDD. GAD patients also showed a significantly longer sleep onset latency and shorter duration of total sleep time and Stage 2 than control subjects. Electroencephalographic sleep recordings, as well as other laboratory tests, may help the clinician to differentiate anxiety from depressive disorders.
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