These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Optical measurements of intracellular pH in intact isolated muscle fibres and muscle growth cones in culture.
    Author: Gillespie JI, Ribchester RR.
    Journal: Q J Exp Physiol; 1988 Nov; 73(6):995-1000. PubMed ID: 3237989.
    Abstract:
    Intracellular pH (pHi) has been measured in intact muscle fibres isolated from the mouse flexor digitorum brevis muscle, using the fluorescence of dicyanohydroquinone as an indicator. The pHi in fibres cultured from 1 to 14 days ranged from 7.0 to 8.1. With time in culture, isolated fibres developed growth cone-like extensions from their ends. These 'myocones' were significantly more alkaline by 0.1-0.2 pH units than the parent fibre. Cultured fibres regulated pHi in response to acid loading with an NH4Cl pulse with recovery rate constants of up to 0.8 pH units/min.
    [Abstract] [Full Text] [Related] [New Search]