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  • Title: [Significance of stenoses of the main bronchus within the scope of congenital abnormalities of the respiratory tract].
    Author: Dietzsch HJ, Wunderlich P, Höhne K, Haink B.
    Journal: Z Erkr Atmungsorgane; 1988; 171(2):111-6. PubMed ID: 3239094.
    Abstract:
    During a period of 23 years (1962 to 1984) we found 197 children with stenoses of the main bronchi among 2,000 bronchological first examinations of children suffering from chronic or recurring bronchopulmonary diseases. In 75 children these stenoses were combined with those of the trachea, in 122 children they were restricted to the main bronchi. The left main bronchus showed an predominant incidence of 85 per cent. Only in 5 cases an extrabronchial cause could be established by anomalous vessels. In the main part of the patients we found intramural stenoses due to congenital circumscribed malazia or to complete aplasia of the bronchial cartilage. The clinical symptoms of a recurring obstructive bronchitis were predominating in nearly 80 per cent of the patients. By follow-up investigations of 65 children with an average duration of 8 years no deaths had occurred. Forty children (65 per cent) were without any complaints and could be physically loaded in a normal way, whereas 21 children showed persistent mild or moderate complaints. In two patients with cystic fibrosis and two others without this basic disorder bronchiectases had developed distal of the stenoses. Bronchological controls after an average follow-up of 3 1/2 years showed in 60 per cent of the children still unchanged stenoses and deforming changes of the bronchial wall distal of the stenoses in contrast to the more favourable clinical findings.
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