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  • Title: Megaloblastic anaemia in a 9-weeks old infant: A case report.
    Author: Afzal T, Ashraf N, Munir S, Tabassum R.
    Journal: J Pak Med Assoc; 2020 May; 70(5):923-925. PubMed ID: 32400755.
    Abstract:
    Megaloblastic anaemia due to vitamin B12 and folic acid deficiency is uncommon in infancy and rarely reported in infants below 3 months of age. We hereby report a case of megaloblastic anaemia in a 9-weeks old infant having fever from 7th week of life. Blood picture showed pancytopenia and diagnosis was confirmed on bone marrow biopsy and serum level of vitamins. Patient positively responded to vitamin B12 and folic acid supplementation. Infants with pancytopenia even younger than 2 months, should also be investigated for vitamin B12 and folate deficiency. Mother of the baby was not antenatally investigated for anaemia. Prompt antenatal diagnosis and treatment of mothers can reduce the incidence in the infants.
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